Feb, 2023 - By WMR
According to new research, vaccination against COVID-19 is linked to lesser heart attacks, strokes, and other cardiac problems in people infected with SARS-CoV-2, the virus associated with COVID-19.
The study, which was released on February 20, 2023 in the Journal of the American College of Cardiology, is the first to investigate the relationship between complete and partial immunization and serious adverse cardiac episodes (MACE) in the United States. Researchers from the Mount Sinai Icahn School of Medicine have accessed the American National COVID Cohort Collaboration database
The researchers used the National COVID Cohort Collaboration (N3C) database, the largest national all-inclusive database on COVID-19. Since its founding in 2020, the N3C has been gathering and integrating data from organizations all around the nation's electronic health records. 1,934,294 individuals totaled in this trial, 217,843 of whom received Johnson & Johnson viral vector technology, Pfizer-BioNTech, Moderna, or mRNA vaccine preparations. Cox proportional probabilities, a statistical technique, were utilized to analyze the correlation between vaccination and MACE.
The researchers discovered a link between comorbid illnesses such as past MACE, type 2 diabetes, high cholesterol, liver disease, and obesity and a decreased chance of complications. The authors of the study also discussed how prior immunization affects cardiovascular events in people with COVID-19. They claimed that there is evidence to show that immunization may be useful in preventing a variety of post-COVID-19 problems despite the fact that they were unable to demonstrate causality.
The study's lead researcher, Joy Jiang, an MD/PhD candidate working in Dr. Nadkarni's group, said they were surprised to find that even partial immunization was associated with a decreased risk of heart disease. Researchers believe that these findings could help increase immunization rates, particularly in persons with coexisting conditions, given the global reach of the SARS-CoV-2 virus.
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