Global Eculizumab Market Research Report 2019

Table of Contents

1 Eculizumab Market Overview 1
1.1 Eculizumab Product Overview 1
1.2 Eculizumab Segment by Types (Product Category) 2
1.2.1 Global Eculizumab Sales and Growth Comparison by Types (2012-2022) 2
1.2.2 Global Eculizumab Sales Market Share (%) by Types in 2016 3
1.3 Global Eculizumab Segment by Applications 3
1.4 Global Eculizumab Market by Regions (2012-2022) 4
1.4.1 Global Eculizumab Market Size and Growth (%) Comparison by Regions (2012-2022) 4
1.4.2 North America Eculizumab Status and Prospect (2012-2022) 5
1.4.3 Asia-Pacific Eculizumab Status and Prospect (2012-2022) 6
1.4.4 Europe Eculizumab Status and Prospect (2012-2022) 7
1.4.5 South America Eculizumab Status and Prospect (2012-2022) 8
1.4.6 Middle East and Africa Eculizumab Status and Prospect (2012-2022) 9
1.5 Global Eculizumab Market Size (2012-2022) 10
1.5.1 Global Eculizumab Revenue Status and Outlook (2012-2022) 10
1.5.2 Global Eculizumab Sales Status and Outlook (2012-2022) 11
1.6 FDA Approvals 11
1.7 Patient Analysis 12
1.7.1 PNH Introduction 12
1.7.2 PNH Patient Analysis 13
1.7.3 aHUS Introduction 13
1.7.4 aHUS Patient Analysis 14
1.8 Eculizumab Clinical Studies 14
1.8.1 New Use of Eculizumab Research 14
1.8.2 Alnylam Research about Eculizumab 15
1.8.3 Amgen Research about Eculizumab 17
1.8.4 EPIRUS Biopharmaceuticals Research about Eculizumab 17
1.8.5 Ra Pharmaceuticals Research about Eculizumab 17
2 Global Eculizumab Market Competition by Manufacturers/Brand 19
2.1 Global Eculizumab Sales (K Vial) and Share by Manufacturers (2012-2017) 19
2.2 Global Eculizumab Revenue and Share by Manufacturers (2012-2017) 21
2.3 Global Eculizumab Average Price (USD/Vial) by Manufacturers (2012-2017) 22
2.4 Manufacturers Eculizumab Headquarter, Sales Area, Product Brands 23
2.5 Eculizumab Market Competitive Situation and Trends 24
2.5.1 Eculizumab Market Concentration Rate 24
2.5.2 Eculizumab Market Share of Top 1 Manufacturers 25
2.5.3 Mergers & Acquisitions, Expansion 26
3 Global Eculizumab Sales, Revenue by Regions (2012-2017) 27
3.1 Global Eculizumab Sales and Market Share by Regions (2012-2017) 27
3.2 Global Eculizumab Revenue and Market Share by Regions (2012-2017) 29
3.3 Global Eculizumab Sales, Revenue, Price and Gross Margin (2012-2017) 31
3.4 North America Eculizumab Sales, Revenue, Price and Gross Margin (2012-2017) 32
3.5 Europe Eculizumab Sales, Revenue, Price and Gross Margin 33
3.6 Asia-Pacific Eculizumab Sales, Revenue, Price and Gross Margin 34
3.7 South America Sales, Revenue, Price and Gross Margin 35
3.8 Middle East and Africa Sales, Revenue, Price and Gross Margin 36
4 Global Eculizumab Sales, Revenue, Price Trend by Types 37
4.1 Global Eculizumab Sales and Market Share by Types (2012-2017) 37
4.2 Global Eculizumab Revenue and Market Share by Types (2012-2017) 39
4.3 Global Eculizumab Price by Type (2012-2017) 40
4.4 Global Eculizumab Sales Growth by Type (2012-2017) 41
5 Global Eculizumab Market Analysis by Applications 42
5.1 Global Eculizumab Sales and Market Share by Applications (2012-2017) 42
5.2 Global Eculizumab Sales Growth Rate by Applications (2012-2017) 44
6 Global Eculizumab Manufacturers Profiles/Analysis 45
6.1 Alexion 45
6.1.1 Company Profile 45
6.1.2 Product Information 46
6.1.3 Production, Price, Cost, Gross, and Revenue 48
7 Eculizumab Manufacturing Cost Analysis 50
7.1 Eculizumab R&D Cost Analysis 50
7.1.1 Clinical Phase Costs 51
7.1.2 Capitalized Costs 52
7.1.3 Eculizumab Key Raw Materials Analysis 53
7.2 Proportion of Manufacturing Cost Structure 54
7.2.1 Raw Materials 54
7.2.2 Labor Cost Analysis 55
7.2.3 Other Costs Analysis 59
7.2.4 Manufacturing Expenses 63
8 Industrial Chain, Sourcing Strategy and Downstream Buyers 64
8.1 Eculizumab Industrial Chain Analysis 64
8.2 Upstream Raw Materials Sourcing 65
8.3 Raw Materials Sources of Eculizumab Major Manufacturers in 2016 65
8.4 Downstream Buyers 65
9 Marketing Strategy Analysis, Distributors/Traders 68
9.1 Marketing Channel 68
9.1.1 Direct Marketing 68
9.1.2 Indirect Marketing 68
9.2 Market Positioning 69
9.2.1 Pricing Strategy 69
9.2.2 Brand Strategy 70
9.2.3 Target Client 70
9.3 Distributors/Traders List 70
10 Market Effect Factors Analysis 72
10.1 Technology Progress/Risk 72
10.2 Consumer Needs/Customer Preference Change 73
10.3 Economic/Political Environmental Change 73
11 Global Eculizumab Market Forecast (2017-2022) 82
11.1 Global Eculizumab Sales, Revenue Forecast (2017-2022) 82
11.1.1 Global Eculizumab Sales and Growth Rate Forecast (2017-2022) 82
11.1.2 Global Eculizumab Revenue and Growth Rate Forecast (2017-2022) 83
11.1.3 Global Eculizumab Price and Trend Forecast (2017-2022) 84
11.2 Global Eculizumab Sales and Revenue Forecast by Regions (2017-2022) 84
11.2.1 North America Eculizumab Sales and Revenue Forecast by Regions (2017-2022) 86
11.2.2 Europe Eculizumab Sales and Revenue Forecast by Regions (2017-2022) 88
11.2.3 Asia-Pacific Eculizumab Sales and Revenue Forecast by Regions (2017-2022) 90
11.2.4 South America Eculizumab Sales and Revenue Forecast by Regions (2017-2022) 92
11.2.5 Middle East and Africa Eculizumab Sales and Revenue Forecast by Regions (2017-2022) 94
11.3 Global Eculizumab Sales Forecast by Type (2017-2022) 95
11.4 Global Eculizumab Sales Forecast by Application (2017-2022) 96
12 Research Findings and Conclusion 98
13 Methodology and Data Source 99
13.1 Methodology/Research Approach 99
13.1.1 Research Programs/Design 99
13.1.2 Market Size Estimation 100
13.1.3 Market Breakdown and Data Triangulation 101
13.2 Data Source 102
13.2.1 Secondary Sources 102
13.2.2 Primary Sources 103
13.3 Disclaimer 104
13.4 Author List 105



List of Tables and Figures

Figure Product Picture of Eculizumab 1
Table Supplemental dose of Soliris after PE/PI 2
Table Global Eculizumab Sales (K Vial) and Growth Rate (%) Comparison by Types (Product Category) (2016-2022) 2
Figure Global Eculizumab Sales Market Share (%) by Types in 2016 3
Table Global Eculizumab Sales (K Vial) Comparison by Applications (2012-2022) 3
Figure Global Eculizumab Sales Market Share (%) by Applications in 2017 4
Table Global Market Eculizumab Revenue (M USD) Comparison by Regions 2012-2022 4
Figure North America Eculizumab Revenue (M USD) and Growth Rate (%) (2012-2022) 5
Figure Asia-Pacific Eculizumab Revenue (M USD) and Growth Rate (%) (2012-2022) 6
Figure Europe Eculizumab Revenue (M USD) and Growth Rate (%) (2012-2022) 7
Figure South America Eculizumab Revenue (M USD) and Growth Rate (%) (2012-2022) 8
Figure Middle East and Africa Eculizumab Revenue (M USD) and Growth Rate (%) (2012-2022) 9
Figure Global Eculizumab Revenue (M USD) Status and Outlook (2012-2022) 10
Figure Global Eculizumab Sales (K Vial) Status and Outlook (2012-2022) 11
Table FDA Approvals Analysis 11
Table Soliris Approval History 12
Table PNH Patient (Unit) Number by Region 13
Table Global PNH Patient Number by Age 13
Table aHUS Patient (Unit) Number by Region 14
Table Global aHUS Patient Number by Age 14
Figure New Pipeline of Eculizumab 14
Table Global Eculizumab Sales (K Vial) of Key Manufacturers (2012-2017) 19
Table Global Eculizumab Sales Share (%) by Manufacturers (2012-2017) 19
Figure 2016 Eculizumab Sales Share (%) by Manufacturers 20
Figure Global Eculizumab Sales (K Vial) and Growth Rate 2012-2017 20
Table Global Eculizumab Revenue (M USD) by Manufacturers (2012-2017) 21
Table Global Eculizumab Revenue Share (%) by Manufacturers (2012-2017) 21
Figure 2016 Global Eculizumab Revenue Share (%) by Manufacturers 21
Figure Global Eculizumab Revenue (M USD) and Growth Rate 2012-2017 22
Table Global Market Eculizumab Average Price (USD/Vial) of Key Manufacturers (2012-2017) 22
Figure Global Market Eculizumab Average Price (USD/Vial) of 2012-2017 23
Table Manufacturers Eculizumab Headquarter and Sales Area 23
Table Manufacturers Eculizumab Product Brands 23
Figure Eculizumab Market Concentration Rate 24
Figure Eculizumab Market Share (%) of Top 1 Manufacturers in 2016 25
Figure Eculizumab Market Share (%) of Top 1 Manufacturers in 2017 25
Table Global Eculizumab Sales (K Vial) by Regions (2012-2017) 27
Table Global Eculizumab Sales Market Share (%) by Regions (2012-2017) 27
Figure Global Eculizumab Sales Market Share (%) by Regions (2012-2017) 28
Figure 2016 Global Eculizumab Sales Market Share (%) by Regions 28
Table Global Eculizumab Revenue (M USD) by Regions (2012-2017) 29
Table Global Eculizumab Revenue Market Share (%) by Regions (2012-2017) 29
Figure Global Eculizumab Revenue Market Share (%) by Regions (2012-2017) 30
Figure 2016 Global Eculizumab Revenue Market Share (%) by Regions 30
Table Global Eculizumab Sales (K Vial), Revenue (M USD), Price (USD/Vial) and Gross Margin (%) (2012-2017) 31
Figure Global Eculizumab Sales (K Vial) and Growth Rate (2012-2017) 31
Table North America Eculizumab Sales (K Vial), Revenue (M USD), Price (USD/Vial) and Gross Margin (%) (2012-2017) 32
Figure North America Eculizumab Sales (K Vial) and Growth Rate (2012-2017) 32
Table Europe Eculizumab Sales (K Vial), Revenue (M USD), Price (USD/Vial) and Gross Margin (%) (2012-2017) 33
Figure Europe Eculizumab Sales (K Vial) and Growth Rate (2012-2017) 33
Table Asia-Pacific Eculizumab Sales (K Vial), Revenue (M USD), Price (USD/Vial) and Gross Margin (%) (2012-2017) 34
Figure Asia-Pacific Eculizumab Sales (K Vial) and Growth Rate (2012-2017) 34
Table South America Eculizumab Sales (K Vial), Revenue (M USD), Price (USD/Vial) and Gross Margin (%) (2012-2017) 35
Figure South America Eculizumab Sales (K Vial) and Growth Rate (2012-2017) 35
Table Middle East and Africa Eculizumab Sales (K Vial), Revenue (M USD), Price (USD/Vial) and Gross Margin (%) (2012-2017) 36
Figure Middle East and Africa Eculizumab Sales (K Vial) and Growth Rate (2012-2017) 36
Table Global Eculizumab Sales (K Vial) by Types (2012-2017) 37
Table Global Eculizumab Sales Share (%) by Types (2012-2017) 37
Figure Sales Market Share (%) of Eculizumab by Types (2012-2017) 38
Figure 2016 Sales Market Share (%) of Eculizumab by Types 38
Table Global Eculizumab Revenue (M USD) by Types (2012-2017) 39
Table Global Eculizumab Revenue Share (%) by Types (2012-2017) 39
Figure Revenue Share (%) of Eculizumab by Types (2012-2017) 39
Figure 2016 Revenue Market Share (%) of Eculizumab by Types 40
Table Global Eculizumab Price (USD/Vial) by Types (2012-2017) 40
Figure Global Eculizumab Sales Growth (%) by Type (2012-2017) 41
Table Global Eculizumab Sales (K Vial) by Applications (2012-2017) 42
Table Global Eculizumab Sales Market Share (%) by Applications (2012-2017) 42
Figure Global Eculizumab Sales Market Share (%) by Applications (2012-2017) 43
Figure Global Eculizumab Sales Market Share (%) by Applications in 2017 43
Table Global Eculizumab Sales Growth Rate (%) by Applications (2012-2017) 44
Figure Global Eculizumab Sales Growth Rate (%) by Applications (2012-2017) 44
Table Alexion Company Profile 45
Figure Eculizumab Product Picture and Specifications of Alexion 46
Table Dosing Recommendations in Patients Less Than 18 Years of Age 46
Figure Pipeline of Alexion 47
Table Eculizumab Production (K Vial), Price (USD/Vial), Cost (USD/Vial), Gross (USD/Vial), Revenue (M USD) and Gross Margin of Alexion 2012-2017 48
Figure Eculizumab Production (K Vial) and Growth Rate of Company One 2012-2017 48
Figure Eculizumab Revenue (M USD) and Growth Rate of Company One 2012-2017 49
Figure Typical Phases from Research to the Market for a Drug Candidate 51
Table Out-of-pocket Preclinical and Clinical Period Cost per Investigational Biopharmaceutical Compound 52
Table Capitalized Preclinical and Clinical Period costs per Investigational Biopharmaceutical Compound 53
Table Raw Material Suppliers Analysis and Contact Information 53
Figure Manufacturing Cost Structure of Eculizumab 54
Figure USA Labor Cost Analysis 2012-2016 55
Figure Cost of Employing a Factory Worker 56
Figure 2016 Estimated Labour Costs for the Whole Economy in Europe 57
Figure Monthly Minimum Wages in Asia 2016 58
Figure China Labor Costs 2013-2016 58
Table Average Price of Electricity to Ultimate Customers 2007-2016 59
Figure Electricity Prices for Household Consumers in 2016 60
Figure Summary of the Driving Assumptions 62
Figure Industrial Electric Rates 2016 (PER KWH) 62
Figure Eculizumab Industrial Chain Analysis 64
Table Major Buyers of Eculizumab 65
Figure Setting Pricing Policy 69
Figure Alexion Global Footprint 71
Figure Eculizumab Phase 3 Studies 72
Figure Global GDP Growth Rate for 2016 74
Figure US GDP 2006-2016 (Billion USD) 75
Figure US CPI Change 2016-2017 75
Figure EU GDP 2006-2016 (Billion USD) 76
Figure EU CPI Change 2012-2016 76
Figure Germany GDP 2006-2016 (Billion USD) 77
Figure Germany CPI Change 2016-2017 77
Figure UK GDP 2006-2016 (Billion USD) 77
Figure UK CPI Change 2016-2017 78
Figure Italy GDP 2006-2016 (Billion USD) 78
Figure Italy CPI Change 2016-2017 79
Figure Japan GDP 2006-2016 (Billion USD) 79
Figure Japan CPI Change 2012-2016 80
Figure China GDP 2006-2016 (Billion USD) 80
Figure China CPI Change 2016-2017 81
Figure Global Eculizumab Sales (K Vial) and Growth Rate (%) Forecast (2017-2022) 82
Figure Global Eculizumab Revenue (M USD) and Growth Rate (%) Forecast (2017-2022) 83
Figure Global Eculizumab Price (USD/Vial) and Trend Forecast (2017-2022) 84
Table Global Eculizumab Sales (K Vial) Forecast by Regions (2017-2022) 84
Figure Global Eculizumab Sales Market Share (%) Forecast by Regions (2017-2022) 85
Figure North America Eculizumab Sales (K Vial) and Growth Rate (%) Forecast (2017-2022) 86
Figure North America Eculizumab Revenue and Growth Rate (%) Forecast (2017-2022) 87
Figure Europe Eculizumab Sales (K Vial) and Growth Rate (%) Forecast (2017-2022) 88
Figure Europe Eculizumab Revenue and Growth Rate (%) Forecast (2017-2022) 89
Figure Asia-Pacific Eculizumab Sales (K Vial) and Growth Rate (%) Forecast (2017-2022) 90
Figure Asia-Pacific Eculizumab Revenue and Growth Rate (%) Forecast (2017-2022) 91
Figure South America Eculizumab Sales (K Vial) and Growth Rate (%) Forecast (2017-2022) 92
Figure South America Eculizumab Revenue and Growth Rate (%) Forecast (2017-2022) 93
Figure Middle East and Africa Eculizumab Sales (K Vial) and Growth Rate (%) Forecast (2017-2022) 94
Figure Middle East and Africa Eculizumab Revenue and Growth Rate (%) Forecast (2017-2022) 95
Table Global Eculizumab Sales (M USD) Forecast by Type (2017-2022) 95
Figure Global Eculizumab Sales Market Share (%) Forecast by Type (2017-2022) 96
Table Global Eculizumab Sales (K Vial) Forecast by Application (2017-2022) 96
Figure Global Eculizumab Sales Forecast by Application (2017-2022) 97
Table Research Programs/Design for This Report 99
Figure Bottom-up and Top-down Approaches for This Report 101
Figure Data Triangulation 102
Table Key Data Information from Secondary Sources 103
Table Key Data Information from Primary Sources 104